Hexachlorophene
目录号: A16217
Wnt/beta-catenin 抑制剂
Hexachlorophene 是一种强效的 KCNQ1/KCNE1 钾通道激活剂，其 EC50 为 4.61 ± 1.29 uM；同时也是 Wnt/β-catenin 信号通路 的抑制剂。
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生物活性
| Discription | Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ?? 1.29 uM; also is an inhibitor of Wnt/beta-catenin signaling. | ||
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产品信息
| 目录号 | A16217 |
|---|---|
| 分子式 | C13H6Cl6O2 |
| 分子量 | 406.9 |
| CAS号 | 70-30-4 |
| SMILES | C1=C(C(=C(C(=C1Cl)Cl)CC2=C(C(=CC(=C2Cl)Cl)Cl)O)O)Cl |
| 其他名称 | Hexachlorofen |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 71 mg/mL (174.48 mM) | |
| Water | Insoluble | ||
| Ethanol | 71 mg/mL (174.48 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.58 mL | 122.88 mL | 245.76 mL |
| 0.5 mM | 4.92 mL | 24.58 mL | 49.15 mL |
| 1 mM | 2.46 mL | 12.29 mL | 24.58 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 70-30-4 | 70-30-4 供应商 | 70-30-4 花费 | 70-30-4 生产商 | 订购 70-30-4 | 70-30-4 代理商