HG-14-10-04
目录号: A16267
ALK/EGFR 抑制剂
HG-14-10-04 是一种效力强大且特异性的 ALK 抑制剂,其 IC50 为 20 nM。
ALK/EGFR 抑制剂
| Discription | HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM. | ||
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| Targets |
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| 目录号 | A16267 |
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| 分子式 | C29H34ClN7O |
| 分子量 | 532.08 |
| CAS号 | 1356962-34-9 |
| SMILES | CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)C5=CNC6=CC=CC=C65)Cl)OC |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 9 mg/mL (16.91 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.79 mL | 93.97 mL | 187.94 mL |
| 0.5 mM | 3.76 mL | 18.79 mL | 37.59 mL |
| 1 mM | 1.88 mL | 9.4 mL | 18.79 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2