HI TOPK 032
目录号: A16042
TOPK 抑制剂
HI-TOPK-032 是一种强效且选择性的 TOPK 抑制剂。在体外实验中,HI-TOPK-032 强烈抑制了 TOPK 激酶活性,但对细胞外信号调节激酶 1(ERK1)、c-jun-NH2-激酶 1 或 p38 激酶活性几乎没有影响。
Discription | HI-TOPK-032 is a potent and selective TOPK inhibitor. In vitro, HI-TOPK-032 strongly suppressed TOPK kinase activity but had little effect on extracellular signal-regulated kinase 1 (ERK1), c-jun-NH2-kinase 1, or p38 kinase activities. |
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目录号 | A16042 |
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分子式 | C20H11N5OS |
分子量 | 369.4 |
CAS号 | 487020-03-1 |
SMILES | O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2 |
其他名称 | HI-TOPK-032, HI-TOPK032, HI-TOPK 032 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 4 mg/mL (10.82 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 27.07 mL | 135.35 mL | 270.71 mL |
0.5 mM | 5.41 mL | 27.07 mL | 54.14 mL |
1 mM | 2.71 mL | 13.54 mL | 27.07 mL |
5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2