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HI TOPK 032

TOPK 抑制剂

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产品目录号: A16042

库存状态:中国现货中国现货

产品名 目录号 价格 数量
HI TOPK 032 5mg A16042-5
¥ 1,200.00
HI TOPK 032 10mg A16042-10
¥ 2,000.00
HI TOPK 032 50mg A16042-50
¥ 8,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

HI-TOPK-032 is a potent and selective TOPK inhibitor. In vitro, HI-TOPK-032 strongly suppressed TOPK kinase activity but had little effect on extracellular signal?Cregulated kinase 1 (ERK1), c-jun??NH2??kinase 1, or p38 kinase activities.

HI TOPK 032

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Chemical Information

目录号 A16042
Mechanism of action Inhibitor
分子量 369.4
化学分子式 C20H11N5OS
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 487020-03-1
Synonyms HI-TOPK-032, HI-TOPK032, HI-TOPK 032
SMILES code O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2
化学名称 N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)thiophene-2-carboxamide

生物活性

Description
HI-TOPK-032 is a potent and selective TOPK inhibitor. In vitro, HI-TOPK-032 strongly suppressed TOPK kinase activity but had little effect on extracellular signal?Cregulated kinase 1 (ERK1), c-jun??NH2??kinase 1, or p38 kinase activities.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.07 mL 135.35 mL 270.71mL
0.5 mM 5.41 mL 27.07 mL 54.14 mL
1 mM 2.71 mL 13.54 mL 27.07 mL
5 mM 0.54 mL 2.71 mL 5.41 mL

*The above data is based on the productmolecular weight 369.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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