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HS-173

促销

PI3K 抑制剂

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产品目录号: A13021

库存状态:中国现货中国现货

产品名 目录号 价格 数量
HS-173 5mg A13021-5
¥ 500.00
HS-173 10mg A13021-10
¥ 800.00
HS-173 25mg A13021-25
¥ 1,600.00
HS-173 50mg A13021-50
¥ 2,800.00
HS-173 10mM * 1mL in DMSO A13021-10mM-D
¥ 1,010.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

HS-173, a novel phosphatidylinositol 3-kinase (PI3K) inhibitor, has anti-tumor activity through promoting apoptosis and inhibiting angiogenesis.

HS-173

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Chemical Information

目录号 A13021
Mechanism of action Inhibitor
分子量 422.1
化学分子式 C21H18N4O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1276110-06-5
Synonyms HS173
SMILES code CCOC(=O)C1=CN=C2N1C=C(C=C2)C3=CC(=CN=C3)NS(=O)(=O)C4=CC=CC=C4
化学名称 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate

生物活性

Description
HS-173, a novel phosphatidylinositol 3-kinase (PI3K) inhibitor, has anti-tumor activity through promoting apoptosis and inhibiting angiogenesis.
Targets
PI3Kα
0.8 nM

溶解性

Solubility (25°C)* In vitro DMSO 84 mg/mL heating (198.83 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.69 mL 118.46 mL 236.91mL
0.5 mM 4.74 mL 23.69 mL 47.38 mL
1 mM 2.37 mL 11.85 mL 23.69 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 422.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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