HSP90-IN-9 is a highly potent and selective inhibitor of the heat shock protein 90 (HSP90). This compound exhibits pronounced fungicidal activity in a dose-dependent manner and effectively inhibits fungal biofilm formation and morphological alterations when used in conjunction with fluconazole (FLC). Additionally, HSP90-IN-9 enhances FLC sensitivity by down-regulating the expression of key resistance-related genes, including ERG11, CDR1, and CDR2, making it a valuable tool for research applications in antifungal resistance studies.
HSP90-IN-9 is a highly potent and selective inhibitor of the heat shock protein 90 (HSP90). This compound exhibits pronounced fungicidal activity in a dose-dependent manner and effectively inhibits fungal biofilm formation and morphological alterations when used in conjunction with fluconazole (FLC). Additionally, HSP90-IN-9 enhances FLC sensitivity by down-regulating the expression of key resistance-related genes, including ERG11, CDR1, and CDR2, making it a valuable tool for research applications in antifungal resistance studies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
