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HTH-01-015

NUAK1 抑制剂

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产品目录号: A16281

库存状态:中国现货中国现货

产品名 目录号 价格 数量
HTH-01-015 5mg A16281-5
¥ 900.00
HTH-01-015 10mg A16281-10
¥ 1,200.00
HTH-01-015 50mg A16281-50
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

HTH-01-015 is a potent and selective inhibitor of NUAK1 (IC50 = 100 nM) and does not affect the activity of a panel of 139 other kinases, including additional AMPK family members.

HTH-01-015

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Chemical Information

目录号 A16281
Mechanism of action Inhibitor
分子量 468.56
化学分子式 C26H28N8O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1613724-42-7
Synonyms HTH01-015, HTH 01-015
SMILES code CC1=C(N(C)C(C2=CC(C=CC=C3)=C3C=C2N4C)=O)C4=NC(NC5=CN(N=C5)C6CCNCC6)=N1
化学名称 4,5,13-trimethyl-2-((1-(piperidin-4-yl)-1H-pyrazol-4-yl)amino)-5,13-dihydro-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one

生物活性

Description
HTH-01-015 is a potent and selective inhibitor of NUAK1 (IC50 = 100 nM) and does not affect the activity of a panel of 139 other kinases, including additional AMPK family members.
Targets
NUAK1 NUAK2
100 nM>10 μM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.34 mL 106.71 mL 213.42mL
0.5 mM 4.27 mL 21.34 mL 42.68 mL
1 mM 2.13 mL 10.67 mL 21.34 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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