Hydroxyzine pamoate
目录号: A17712
Histamine H1 receptor 拮抗剂
Hydroxyzine pamoate 是一种组胺H1受体拮抗剂,有效治疗慢性荨麻疹、皮炎和由组胺介导的瘙痒。与其主要代谢物西替利嗪不同的是,它会引起嗜睡。
Discription | Hydroxyzine pamoate is an histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. |
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目录号 | A17712 |
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分子式 | C44H43ClN2O8 |
分子量 | 763.28 |
CAS号 | 10246-75-0 |
SMILES | ClC1=CC=C(C(N2CCN(CCOCCO)CC2)C3=CC=CC=C3)C=C1.O=C(C4=C(O)C(CC5=C6C=CC=CC6=CC(C(O)=O)=C5O)=C7C=CC=CC7=C4)O |
其他名称 | Hydroxyzine pamoate |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 93 mg/mL (121.84 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 13.1 mL | 65.51 mL | 131.01 mL |
0.5 mM | 2.62 mL | 13.1 mL | 26.2 mL |
1 mM | 1.31 mL | 6.55 mL | 13.1 mL |
5 mM | 0.26 mL | 1.31 mL | 2.62 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2