Ibutilide fumarate
目录号: A11750
Ibutilide 是一种 Class III 抗心律失常药物,用于治疗近期发作的心房颤动和心房扑动的急性心律转复为窦性心律。它通过诱导缓慢的内向钠电流来发挥其抗心律失常效果,这种作用延长了心肌细胞的动作电位和不应期(生理学)。
Discription | Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period (physiology) of myocardial cells. |
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目录号 | A11750 |
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分子式 | (C20H36N2O3S)2.C4H4O |
分子量 | 885.2 |
CAS号 | 122647-32-9 |
SMILES | CCCCCCCN(CC)CCCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.CCCCCCCN(CC)CCCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.C(=C/C(=O)O)\C(=O)O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 88 mg/mL (99.4 mM) | |
Water | 88 mg/mL (99.4 mM) | ||
Ethanol | 88 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 11.3 mL | 56.48 mL | 112.97 mL |
0.5 mM | 2.26 mL | 11.3 mL | 22.59 mL |
1 mM | 1.13 mL | 5.65 mL | 11.3 mL |
5 mM | 0.23 mL | 1.13 mL | 2.26 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2