Icariin

目录号: A10464

PDE5 inhibitor

Icariin Chemical Structure

CAS NO. 489-32-7

Icariin is inhibitory to all three PDE5 isoforms that inhibits PDE5A1, A2, and A3 with an IC50 value of 1.0, 0.75, and 1.1 microM, respectively.

库存: 现货

规格 价格 数量
50 mg
¥ 600.00
100 mg
¥ 550.00
250 mg
¥ 900.00
500 mg
¥ 1,550.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Icariin is inhibitory to all three PDE5 isoforms that inhibits PDE5A1, A2, and A3 with an IC50 value of 1.0, 0.75, and 1.1 microM, respectively.
Targets
PDE5
0.432 μM
In vitro DMSO 50 mg/mL (73.89 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.78 mL 73.89 mL 147.78 mL
0.5 mM 2.96 mL 14.78 mL 29.56 mL
1 mM 1.48 mL 7.39 mL 14.78 mL
5 mM 0.3 mL 1.48 mL 2.96 mL

*The above data is based on the productmolecular weight 676.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10464
MECHANISM OF ACTION Inhibitor
M. Wt 676.7
Formula C33H40O15
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 489-32-7
Synonyms N/A
SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O

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