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Icatibant

Icatibant

Name: Icatibant
SKU: A18074

目录号: A18074

Bradykinin B2 receptors antagonist

Icatibant Chemical Structure

CAS NO. 130308-48-4

Icatibant (HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.

库存：现货

规格	价格	数量
1 mg	￥ 2,500.00
5 mg	￥ 5,000.00
10 mg	￥ 7,000.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

Icatibant (HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	7.67 mL	38.33 mL	76.66 mL
0.5 mM	1.53 mL	7.67 mL	15.33 mL
1 mM	0.77 mL	3.83 mL	7.67 mL
5 mM	0.15 mL	0.77 mL	1.53 mL

*The above data is based on the productmolecular weight 1304.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18074
作用机制	Antagonist (拮抗剂)
M. Wt	1304.52
Formula	C59H89N19O13S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	130308-48-4
Synonyms	Firazyr
SMILES	N=C(N)NC(C(C1NCC2=C(C=CC=C2)C1)=O)CC[C@@H](C(O)=O)N(C([C@H](CO)N(C(CN(C([C@H]3N(C([C@H](CCCNC(N)=N)NC([C@@H](CCCNC(N)=N)N)=O)=O)CCC3)=O)C(C4NC[C@H](O)C4)=O)=O)C([C@H](CC5=CC=CS5)N)=O)=O)C(C6N[C@@]7([H])CCCC[C@@]7([H])C6)=O