iCRT 14
目录号: A16218
CRT 抑制剂
iCRT 14 是一种新型的强效 β-连环蛋白响应性转录(CRT)抑制剂(在 Wnt 通路活性测定中的 IC50 为 40.3 nM)。
Discription | iCRT 14 is a novel potent inhibitor of beta-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). |
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目录号 | A16218 |
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分子式 | C21H17N3O2S |
分子量 | 375.44 |
CAS号 | 677331-12-3 |
SMILES | CC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)N(C(=O)S3)C4=CC=CC=C4 |
其他名称 | iCRT14, iCRT-14 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 35 mg/mL (93.22 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.64 mL | 133.18 mL | 266.35 mL |
0.5 mM | 5.33 mL | 26.64 mL | 53.27 mL |
1 mM | 2.66 mL | 13.32 mL | 26.64 mL |
5 mM | 0.53 mL | 2.66 mL | 5.33 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2