IDF-11774

Name: IDF-11774
SKU: A16845
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A16845

HIF-1 抑制剂

生物活性描述 IDF-11774 是一种低氧诱导因子-1 (HIF-1) 抑制剂。它降低了 HIF-1α 的 HRE-荧光素酶活性（IC50 = 3.65 μM），并在低氧条件下阻断了 HCT116 人类结肠癌细胞中的 HIF-1α 积累。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
2mg	¥595.00	现货
5mg	¥735.00	现货
10mg	¥1,330.00	现货
25mg	¥2,240.00	现货
50mg	¥3,360.00	现货
100mg	¥4,935.00	现货
*10mM 1mL in DMSO**	¥595.00	现货
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Data Sheet

SDS

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生物活性

Discription	Biological Activity Description IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor. It reduces the HRE-luciferase activity of HIF-1α (IC50 = 3.65 μM) and blocks HIF-1α accumulation under hypoxia in HCT116 human colon cancer cells.

产品信息

目录号	A16845
分子式	C23H32N2O2
分子量	368.51
CAS号	1429054-28-3
SMILES	O=C(N1CCN(C)CC1)COC2=CC=C(C34C[C@H]5C[C@@](C4)([H])C[C@H](C5)C3)C=C2
其他名称	IDF11774, IDF 11774
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	13 mg/mL (35.27 mM)
	Water	Insoluble
	Ethanol	4 mg/mL (10.85 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.14 mL	135.68 mL	271.36 mL
0.5 mM	5.43 mL	27.14 mL	54.27 mL
1 mM	2.71 mL	13.57 mL	27.14 mL
5 mM	0.54 mL	2.71 mL	5.43 mL

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