IITZ-01
目录号: A20192
Lysosomotropic autophagy 抑制剂
IITZ-01 是一种强效的溶酶体自噬抑制剂，具有单药抗肿瘤活性，对 PI3Kγ 的 IC50 为 2.62 μM。
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生物活性
| Discription | IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ. | ||
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产品信息
| 目录号 | A20192 |
|---|---|
| 分子式 | C26H23FN8O |
| 分子量 | 482.51 |
| CAS号 | 1807988-47-1 |
| SMILES | FC1=CC=C(NC2=NC(N3CCOCC3)=NC(NC4=CC=C(C5=NC6=CC=CC=C6N5)C=C4)=N2)C=C1 |
| 其他名称 | IITZ 01; IITZ01; Autophagy inhibitor IITZ-01 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 89 mg/mL (184.44 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.72 mL | 103.62 mL | 207.25 mL |
| 0.5 mM | 4.14 mL | 20.72 mL | 41.45 mL |
| 1 mM | 2.07 mL | 10.36 mL | 20.72 mL |
| 5 mM | 0.41 mL | 2.07 mL | 4.14 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1807988-47-1 | 1807988-47-1 供应商 | 1807988-47-1 花费 | 1807988-47-1 生产商 | 订购 1807988-47-1 | 1807988-47-1 代理商