IKK-16

Name: IKK-16
SKU: A12836

目录号: A12836

IKK 抑制剂

Product Citations (1)

IKK-16 Chemical Structure

CAS NO. 873225-46-8

IKK 16是针对IKK-2，IKK复合物和IKK-1的选择性IκB激酶（IKK）抑制剂，IC50分别为40 nM，70 nM和200 nM。

库存：现货

规格	价格	数量
10 mg	￥ 800.00
25 mg	￥ 1,500.00
50 mg	￥ 2,200.00
100 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 980.00

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生物活性

IKK 16是针对IKK-2，IKK复合物和IKK-1的选择性IκB激酶（IKK）抑制剂，IC50分别为40 nM，70 nM和200 nM。

靶点信息

IKK2 (Cell-free assay)	IKK complex (Cell-free assay)	IKK1 (Cell-free assay)
40 nM	70 nM	200 nM

溶解度 *

In vitro (25°C)	DMSO	95 mg/mL (196.42 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.68 mL	103.38 mL	206.77 mL
0.5 mM	4.14 mL	20.68 mL	41.35 mL
1 mM	2.07 mL	10.34 mL	20.68 mL
5 mM	0.41 mL	2.07 mL	4.14 mL

*The above data is based on the productmolecular weight 483.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12836
作用机制	Inhibitor (抑制剂)
M. Wt	483.63
Formula	C28H29N5OS
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	873225-46-8
Synonyms	IKK 16, IKK16
SMILES	C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5