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IKK epsilon-IN-1

IKK-?? 抑制剂

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产品目录号: A16298

库存状态:中国现货中国现货

产品名 目录号 价格 数量
IKK epsilon-IN-1 5mg A16298-5
¥ 3,200.00
IKK epsilon-IN-1 10mg A16298-10
¥ 4,800.00
IKK epsilon-IN-1 50mg A16298-50
¥ 14,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

IKK epsilon-IN-1 is a potent IKKε inhibitor; inhibit the in-situ IKK ε-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.

IKK epsilon-IN-1

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Chemical Information

目录号 A16298
Mechanism of action Inhibitor
分子量 457.52
化学分子式 C26H27N5O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1292310-49-6
Synonyms N/A
SMILES code C1COCCC1OC2=C(C=C(C=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCOCC5)C#N
化学名称 5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-2-(oxan-4-yloxy)benzonitrile

生物活性

Description
IKK epsilon-IN-1 is a potent IKKε inhibitor; inhibit the in-situ IKK ε-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.86 mL 109.28 mL 218.57mL
0.5 mM 4.37 mL 21.86 mL 43.71 mL
1 mM 2.19 mL 10.93 mL 21.86 mL
5 mM 0.44 mL 2.19 mL 4.37 mL

*The above data is based on the productmolecular weight 457.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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