IKK epsilon-IN-1
目录号: A16298
IKK-ε 抑制剂
IKK epsilon-IN-1 是一种强效的 IKKε 抑制剂;能够抑制原位 IKKε-介导的 IRF3 磷酸化,其 IC50 值小于约 100 nM。
Discription | IKK epsilon-IN-1 is a potent IKKε inhibitor; inhibit the in-situ IKK ε-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM. | ||
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Targets |
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目录号 | A16298 |
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分子式 | C26H27N5O3 |
分子量 | 457.52 |
CAS号 | 1292310-49-6 |
SMILES | C1COCCC1OC2=C(C=C(C=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCOCC5)C#N |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 57 mg/mL (124.58 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.86 mL | 109.28 mL | 218.57 mL |
0.5 mM | 4.37 mL | 21.86 mL | 43.71 mL |
1 mM | 2.19 mL | 10.93 mL | 21.86 mL |
5 mM | 0.44 mL | 2.19 mL | 4.37 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2