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Ilorasertib

Ilorasertib

Name: Ilorasertib
SKU: A20982

目录号: A20982

ATP-competitive multitargeted kinase inhibitor

Ilorasertib Chemical Structure

CAS NO. 1227939-82-3

Ilorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 630.00
5 mg	￥ 1,890.00
10 mg	￥ 3,220.00
50 mg	￥ 9,660.00

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生物活性

Ilorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.47 mL	102.35 mL	204.69 mL
0.5 mM	4.09 mL	20.47 mL	40.94 mL
1 mM	2.05 mL	10.23 mL	20.47 mL
5 mM	0.41 mL	2.05 mL	4.09 mL

*The above data is based on the productmolecular weight 488.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20982
作用机制	Inhibitor (抑制剂)
M. Wt	488.54
Formula	C25H21FN6O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1227939-82-3
Synonyms	ABT-348, ABT348, ABT 348
SMILES	O=C(NC1=CC=CC(F)=C1)NC2=CC=C(C3=CSC4=C3C(N)=NC=C4C5=CN(CCO)N=C5)C=C2