Ilorasertib
目录号: A20982
ATP-competitive multitargeted kinase 抑制剂
Ilorasertib (ABT-348) 是一种强效且与ATP竞争的多靶点激酶抑制剂,它能抑制 Aurora C、Aurora B 和 Aurora A,其半抑制浓度(IC50)分别为1纳摩尔、7纳摩尔和120纳摩尔。
| Discription | Ilorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively. | ||
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| 目录号 | A20982 |
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| 分子式 | C25H21FN6O2S |
| 分子量 | 488.54 |
| CAS号 | 1227939-82-3 |
| SMILES | O=C(NC1=CC=CC(F)=C1)NC2=CC=C(C3=CSC4=C3C(N)=NC=C4C5=CN(CCO)N=C5)C=C2 |
| 其他名称 | ABT-348, ABT348, ABT 348 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2