IM-12

目录号: A14196

GSK-3β inhibitor

IM-12 Chemical Structure

CAS NO. 1129669-05-1

IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.

库存: 现货

规格 价格 数量
10 mg
¥ 600.00
25 mg
¥ 1,200.00
50 mg
¥ 2,000.00
100 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 820.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.
Targets
GSK-3β
53 nM
In vitro DMSO 75 mg/mL (198.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol 10 mg/mL heating (26.49 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.5 mL 132.48 mL 264.96 mL
0.5 mM 5.3 mL 26.5 mL 52.99 mL
1 mM 2.65 mL 13.25 mL 26.5 mL
5 mM 0.53 mL 2.65 mL 5.3 mL

*The above data is based on the productmolecular weight 377.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14196
MECHANISM OF ACTION Inhibitor
M. Wt 377.41
Formula C22H20FN3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1129669-05-1
Synonyms IM12, IM 12
SMILES CC1=C(C2=CC=CC=C2N1)C3=C(C(=O)N(C3=O)C)NCCC4=CC=C(C=C4)F

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