IMAB027 (ASP1650) is a monoclonal antibody specifically targeting CLDN6 (Claudin 6), a tight junction membrane protein. CLDN6 is aberrantly expressed in a range of human cancers, particularly in ovarian cancers. This antibody has demonstrated potent anti-tumor activity and can induce apoptosis in CLDN6-positive ovarian and testicular cancer cell lines. IMAB027 is utilized primarily in research focused on the pathological roles of CLDN6 in cancer and the therapeutic potential of targeting this protein in oncology.
IMAB027 (ASP1650) is a monoclonal antibody specifically targeting CLDN6 (Claudin 6), a tight junction membrane protein. CLDN6 is aberrantly expressed in a range of human cancers, particularly in ovarian cancers. This antibody has demonstrated potent anti-tumor activity and can induce apoptosis in CLDN6-positive ovarian and testicular cancer cell lines. IMAB027 is utilized primarily in research focused on the pathological roles of CLDN6 in cancer and the therapeutic potential of targeting this protein in oncology.
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