IDO5L (INCB024360 analog)
目录号: A13004
IDO1 抑制剂
INCB024360 是一种口服可用的羟基酰胺和吲哚胺2,3-双加氧酶(IDO1)抑制剂,具有潜在的免疫调节和抗肿瘤活性。
Discription | INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities. | |||||
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Cell Research |
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目录号 | A13004 |
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分子式 | C9H7ClFN5O2 |
分子量 | 271.63 |
CAS号 | 914471-09-3 |
SMILES | C1=CC(=C(C=C1N/C(=C\2/C(=NON2)N)/N=O)Cl)F |
其他名称 | INCB-024360, INCB 024360 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 46 mg/mL (169.34 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 46 mg/mL (169.34 mM) | ||
In vivo | 5% DMSO+45% PEG 300+ddH2O | 20 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 36.81 mL | 184.07 mL | 368.15 mL |
0.5 mM | 7.36 mL | 36.81 mL | 73.63 mL |
1 mM | 3.68 mL | 18.41 mL | 36.81 mL |
5 mM | 0.74 mL | 3.68 mL | 7.36 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2