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INCB024360 analog

促销

IDO1 抑制剂

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产品目录号: A13004

库存状态:中国现货中国现货

产品名 目录号 价格 数量
INCB024360 analog 5mg A13004-5
¥ 550.00
INCB024360 analog 10mg A13004-10
¥ 800.00
INCB024360 analog 25mg A13004-25
¥ 1,500.00
INCB024360 analog 50mg A13004-50
¥ 2,400.00
INCB024360 analog 10mM * 1mL in DMSO A13004-10mM-D
¥ 1,020.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities.

INCB024360 analog

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Chemical Information

目录号 A13004
Mechanism of action Inhibitor
分子量 271.63
化学分子式 C9H7ClFN5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 914471-09-3
Synonyms INCB-024360, INCB 024360
SMILES code C1=CC(=C(C=C1N/C(=C\2/C(=NON2)N)/N=O)Cl)F
化学名称 4-amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide

生物活性

Description
INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities.
Targets
IDO1
67 nM

溶解性

Solubility (25°C)* In vitro DMSO 54 mg/mL (198.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol 54 mg/mL heating (198.79 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.81 mL 184.07 mL 368.15mL
0.5 mM 7.36 mL 36.81 mL 73.63 mL
1 mM 3.68 mL 18.41 mL 36.81 mL
5 mM 0.74 mL 3.68 mL 7.36 mL

*The above data is based on the productmolecular weight 271.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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