INCB053914 phosphate
目录号: A21444
Pim 抑制剂
INCB053914 磷酸盐是一种从专利 WO 2017044730 A1 提取的 Pim 抑制剂,化合物 1;具有小于 35 nM 的 IC50。
Discription | INCB053914 phosphate is an inhibitor of Pim extracted from patent WO 2017044730 A1, compound 1; has an IC50 of less than 35 nM. | ||
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Targets |
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目录号 | A21444 |
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分子式 | C26H29F3N5O7P |
分子量 | 611.51 |
CAS号 | 2088852-47-3 |
SMILES | O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.OP(O)(O)=O |
其他名称 | INCB 053914, INCB-053914 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 48 mg/mL (78.49 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 16.35 mL | 81.76 mL | 163.53 mL |
0.5 mM | 3.27 mL | 16.35 mL | 32.71 mL |
1 mM | 1.64 mL | 8.18 mL | 16.35 mL |
5 mM | 0.33 mL | 1.64 mL | 3.27 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2