INCB39110 (Itacitinib)

Name: INCB39110 (Itacitinib)
SKU: A14390
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A14390

JAK1 抑制剂

1 篇发表文献

INCB39110 是一种强效的 JAK1 酪氨酸激酶抑制剂，目前正在进行第二阶段试验，用于治疗类风湿性关节炎、骨髓纤维化、类风湿性关节炎和斑块型银屑病。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥420.00	现货
5mg	¥735.00	现货
10mg	¥1,260.00	现货
25mg	¥2,345.00	现货
50mg	¥3,955.00	现货
100mg	¥5,705.00	现货
500mg	¥11,375.00	现货
*10mM 1mL in DMSO**	¥910.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用INCB39110 (Itacitinib)发表的1篇文献

Czech J, .et al. , Leukemia, 2018, Nov 23 PMID: 30470838

生物活性

Discription

INCB39110 is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis.

Targets

Target	Value

产品信息

目录号	A14390
分子式	C26H23F4N9O
分子量	553.51
CAS号	1334298-90-6
SMILES	N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(C5CCN(C(C6=C(F)C(C(F)(F)F)=NC=C6)=O)CC5)C1
其他名称	INCB 39110, INCB-39110, INCB039110, INCB-039110, INCB 039110
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	88 mg/mL (158.98 mM)
	Water	Insoluble
	Ethanol	88 mg/mL (158.98 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.07 mL	90.33 mL	180.67 mL
0.5 mM	3.61 mL	18.07 mL	36.13 mL
1 mM	1.81 mL	9.03 mL	18.07 mL
5 mM	0.36 mL	1.81 mL	3.61 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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