INCB39110 (Itacitinib)

目录号: A14390

JAK1 抑制剂

INCB39110 (Itacitinib) Chemical Structure

CAS NO. 1334298-90-6

INCB39110 is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis.

库存: 现货

规格 价格 数量
5 mg
¥ 1,250.00
10 mg
¥ 2,250.00
25 mg
¥ 4,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

INCB39110 is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.07 mL 90.33 mL 180.67 mL
0.5 mM 3.61 mL 18.07 mL 36.13 mL
1 mM 1.81 mL 9.03 mL 18.07 mL
5 mM 0.36 mL 1.81 mL 3.61 mL

*The above data is based on the productmolecular weight 553.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14390
MECHANISM OF ACTION Inhibitor
M. Wt 553.51
Formula C26H23F4N9O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1334298-90-6
Synonyms INCB 39110, INCB-39110, INCB039110, INCB-039110, INCB 039110
SMILES N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(C5CCN(C(C6=C(F)C(C(F)(F)F)=NC=C6)=O)CC5)C1

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