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INCB8761 (PF-4136309)

CCR2 拮抗剂

158 Customer Reviews
产品目录号: A11136

库存状态:中国现货中国现货

产品名 目录号 价格 数量
INCB8761 5mg A11136-5
¥ 1,500.00
INCB8761 10mg A11136-10
¥ 2,700.00
INCB8761 50mg A11136-50
¥ 8,000.00
INCB8761 100mg A11136-100
¥ 14,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

INCB8761(PF-4136309) is a potent, selective, and orally bioavailable CCR2 antagonist.

INCB8761 (PF-4136309)

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Chemical Information

目录号 A11136
Mechanism of action Antagonist
分子量 568.6
化学分子式 C29H31F3N6O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 857679-55-1, 1341224-83-6
Synonyms INCB-8761,PF4136309
SMILES code C1CN(C[C@H]1NC2CCC(CC2)(C3=NC=C(C=C3)C4=NC=CC=N4)O)C(=O)CNC(=O)C5=CC(=CC=C5)C(F)(F)F
化学名称 N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

生物活性

Description
INCB8761(PF-4136309) is a potent, selective, and orally bioavailable CCR2 antagonist.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.59 mL 87.94 mL 175.87mL
0.5 mM 3.52 mL 17.59 mL 35.17 mL
1 mM 1.76 mL 8.79 mL 17.59 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 568.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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