Trusted by 10,000+ Scientists since 2006
微信关注
申请试用装

Indirubin

促销

CDK & GSK-3?? 抑制剂

0 Customer Reviews
产品目录号: A10471

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Indirubin 5mg A10471-5
¥ 400.00
Indirubin 25mg A10471-25
¥ 1,200.00
Indirubin 50mg A10471-50
¥ 2,000.00
Indirubin 100mg A10471-100
¥ 3,500.00
Indirubin 10mM * 1mL in DMSO A10471-10mM-D
¥ 800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Indirubin, the active constituent of a Chinese antileukaemia medicine, is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM.

Indirubin

双击上述图片即可查看完整大小

缩小
放大

更多视图

顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A10471
Mechanism of action Inhibitor
分子量 262.3
化学分子式 C16H10N2O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 479-41-4
Synonyms Couroupitine B, Indigo red
SMILES code C1=CC=C2C(=C1)/C(=C\3/C(=O)C4=CC=CC=C4N3)/C(=O)N2
化学名称 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one

生物活性

Description
Indirubin, the active constituent of a Chinese antileukaemia medicine, is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM.
Targets
Target Value
GSK-3βIC50: 0.6μM
CDK2/CyclinAIC50: 2.2μM
CDK5/p35IC50: 5.5μM
CDK1/CyclinBIC50: 10μM
C-RafIC50: >10μM
CDK4/CyclinD1IC50: 12μM
c-SrcIC50: 18μM
ERK2IC50: 43μM
ERK1IC50: >100μM
MAPKKIC50: >100μM
PKCαIC50: >100μM
PKCβ1IC50: >100μM
PKCβ2IC50: >100μM
PKCγIC50: >100μM
PKCδIC50: >100μM
PKCεIC50: >100μM
PKCηIC50: >100μM
PKCζIC50: >100μM
c-AblIC50: >1000μM

溶解性

Solubility (25°C)* In vitro DMSO 53 mg/mL (202.08 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.12 mL 190.62 mL 381.24mL
0.5 mM 7.62 mL 38.12 mL 76.25 mL
1 mM 3.81 mL 19.06 mL 38.12 mL
5 mM 0.76 mL 3.81 mL 7.62 mL

*The above data is based on the productmolecular weight 262.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Similar product(s)


Keywords:购买 Indirubin | Indirubin 供应商 | 订购 Indirubin | Indirubin 价格 | Indirubin 生产商 | 订单 Indirubin | Indirubin 代理商 | 购买 479-41-4 | 479-41-4 供应商 | 订购 479-41-4 | 479-41-4 价格 | 479-41-4 生产商 | 订单 479-41-4 | 479-41-4 代理商|buy Indirubin | Indirubin Supplier | purchase Indirubin | Indirubin cost | Indirubin manufacturer | order Indirubin | Indirubin distributor | buy 479-41-4 | 479-41-4 Supplier | purchase 479-41-4 | 479-41-4 cost | 479-41-4 manufacturer | order 479-41-4 | 479-41-4 distributor