Indomethacin (Indocid, Indocin)

目录号: A10474

COX inhibitor

Indomethacin (Indocid, Indocin) Chemical Structure

CAS NO. 53-86-1

Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.

库存: 现货

规格 价格 数量
100 mg
¥ 500.00
250 mg
¥ 1,000.00
500 mg
¥ 1,800.00
1000 mg
¥ 3,300.00
10mM * 1mL in DMSO
¥ 610.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.
Targets
COX1 COX-2
0.28 μM14 μM
In vitro DMSO 72 mg/mL (201.23 mM)
Water <1 mg/mL (<1 mM)
Ethanol 24 mg/mL (67.07 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.95 mL 139.75 mL 279.49 mL
0.5 mM 5.59 mL 27.95 mL 55.9 mL
1 mM 2.79 mL 13.97 mL 27.95 mL
5 mM 0.56 mL 2.79 mL 5.59 mL

*The above data is based on the productmolecular weight 357.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10474
MECHANISM OF ACTION Inhibitor
M. Wt 357.79
Formula C19H16ClNO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 53-86-1
Synonyms Indomethacin, Indochron E-R, Indocin-SR, Indocid, Indocin
SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

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