Indomethacin (Indocid, Indocin)

Name: Indomethacin (Indocid, Indocin)
SKU: A10474

目录号: A10474

COX 抑制剂

Product Citations (3)

Indomethacin (Indocid, Indocin) Chemical Structure

CAS NO. 53-86-1

Indomethacin (Indocid, Indocin)是一种非选择性COX1和COX2抑制剂，IC50分别为0.1 μg/mL和5 μg/mL。吲哚美辛(吲哚满，吲哚满)是一种非甾体抗炎药，通常用于减轻发热、疼痛、僵硬和肿胀。

库存：现货

规格	价格	数量
500 mg	￥ 450.00
10mM * 1mL in DMSO	￥ 610.00

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生物活性

靶点信息

COX1	COX-2
0.28 μM	14 μM

溶解度 *

In vitro (25°C)	DMSO	63 mg/mL (176.08 mM)
	Water	Insoluble
	Ethanol	21 mg/mL (58.69 mM)
In vivo	5% DMSO+30% PEG 300+5% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.95 mL	139.75 mL	279.49 mL
0.5 mM	5.59 mL	27.95 mL	55.9 mL
1 mM	2.79 mL	13.97 mL	27.95 mL
5 mM	0.56 mL	2.79 mL	5.59 mL

*The above data is based on the productmolecular weight 357.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10474
作用机制	Inhibitor (抑制剂)
M. Wt	357.79
Formula	C19H16ClNO4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	53-86-1
Synonyms	Indomethacin, Indochron E-R, Indocin-SR, Indocid, Indocin
SMILES	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O