INK 128 (MLN0128)

Name: INK 128 (MLN0128)
SKU: A11461
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A11461

mTOR 抑制剂

1 篇发表文献

INK 128 是一种 TORC1/2 抑制剂，同时也是一种可口服的抑制剂，针对 raptor-mTOR (TOR 复合体 1 或 TORC1) 和 rictor-mTOR (TOR 复合体 2 或 TORC2)，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥490.00	现货
10mg	¥630.00	现货
25mg	¥1,085.00	现货
50mg	¥1,680.00	现货
100mg	¥2,520.00	现货
500mg	¥6,125.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用INK 128 (MLN0128)发表的1篇文献

Ashlyn Parkhurst, .et al. , Cell Death Dis, 2022, Apr 28;13(4):410 PMID: 35484114

生物活性

Discription

INK 128 is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11461
分子式	C15H15N7O
分子量	309.3
CAS号	1224844-38-5
SMILES	CC(C)N1C2=C(C(=N1)C3=CC4=C(C=C3)OC(=N4)N)C(=NC=N2)N
其他名称	INK128, INK-128
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	58 mg/mL (187.5 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (6.46 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.33 mL	161.66 mL	323.31 mL
0.5 mM	6.47 mL	32.33 mL	64.66 mL
1 mM	3.23 mL	16.17 mL	32.33 mL
5 mM	0.65 mL	3.23 mL	6.47 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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