Ipatasertib dihydrochloride

Name: Ipatasertib dihydrochloride
SKU: A21734
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A21734

pan-Akt 抑制剂

Ipatasertib dihydrochloride（GDC-0068 dihydrochloride）是一种高度选择性的全Akt抑制剂，针对Akt1/2/3，其IC50分别为5/18/8 nM，对PKA的选择性高达620倍。

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Grouped product items
规格	价格	库存
2mg	¥280.00	现货
5mg	¥455.00	现货
10mg	¥700.00	现货
50mg	¥2,100.00	现货
100mg	¥3,255.00	现货
200mg	¥5,460.00	现货
500mg	¥10,990.00	现货
1g	¥19,075.00	现货
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Data Sheet

SDS

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生物活性

Discription

Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.

Targets

Target	Value

产品信息

目录号	A21734
分子式	C24H34Cl3N5O2
分子量	530.92
CAS号	1396257-94-5
SMILES	ClC1=CC=C([C@@H](CNC(C)C)C(N2CCN(C3=C([C@H](C)C[C@H]4O)C4=NC=N3)CC2)=O)C=C1.[H]Cl.[H]Cl
其他名称	GDC-0068 (dihydrochloride), GDC0068, GDC0068; RG-7440 dihydrochloride, RG7440, RG 7440
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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