IPI-3063
目录号: A16800
selective p110δ 抑制剂
IPI-3063 是一种强效且选择性的 p110δ 抑制剂,其生化 IC50 为 2.5±1.2 nM,对其他 I 类 PI3K 同型酶(p110α、p110β、p110γ)的 IC50 值至少高出 400 倍。
Discription | IPI-3063 is a potent and selective p110δ inhibitor with biochemical IC50 of 2.5??1.2 nM and IC50 values for the other class I PI3K isoforms (p110α, p110β, p110γ) are at least 400-fold higher. | ||
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Targets |
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目录号 | A16800 |
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分子式 | C25H25N7O2 |
分子量 | 455.51 |
CAS号 | 1425043-73-7 |
SMILES | O=C1N(C)C=C(C2=CC=CC(C=C([C@@H](NC3=C(C#N)C(N)=NC=N3)C)N4C(C)C)=C2C4=O)C=C1 |
其他名称 | IPI3063, IPI 3063 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 83 mg/mL (182.21 mM) | |
Water | Insoluble | ||
Ethanol | 11 mg/mL (24.15 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.95 mL | 109.77 mL | 219.53 mL |
0.5 mM | 4.39 mL | 21.95 mL | 43.91 mL |
1 mM | 2.2 mL | 10.98 mL | 21.95 mL |
5 mM | 0.44 mL | 2.2 mL | 4.39 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2