Eganelisib (IPI-549)
目录号: A16332
PI3Kγ 抑制剂
IPI-549 是一种强效且选择性的 PI3Kγ 抑制剂,IC50 为 16 nM。
| Discription | IPI-549 is a potent and selective PI3Kγ Inhibitor with IC50 of 16 nM. | |||||
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| 目录号 | A16332 |
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| 分子式 | C30H24N8O2 |
| 分子量 | 528.56 |
| CAS号 | 1693758-51-8 |
| SMILES | O=C1N(C2=CC=CC=C2)C([C@@H](NC(C3=C(N=CC=C4)N4N=C3N)=O)C)=CC5=CC=CC(C#CC6=CN(C)N=C6)=C51 |
| 其他名称 | IPI549, IPI 549 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 87 mg/mL (164.6 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (13.24 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.92 mL | 94.6 mL | 189.19 mL |
| 0.5 mM | 3.78 mL | 18.92 mL | 37.84 mL |
| 1 mM | 1.89 mL | 9.46 mL | 18.92 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.78 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2