IQ 3

Name: IQ 3
SKU: A16036
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A16036

JNK3 抑制剂

IQ 3 是一种选择性的 JNK3 抑制剂（对 JNK3、JNK1 和 JNK2 的 Kd 值分别为 66、240 和 290 nM）。在 THP1-Blue 细胞中抑制 NF-kB/AP1 转录活性（IC50 = 1.4 μM）。还能在体外抑制 TNF-α 和 IL-6 的产生。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥490.00	现货
10mg	¥770.00	现货
25mg	¥1,575.00	现货
50mg	¥2,520.00	现货
100mg	¥3,780.00	现货
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Data Sheet

SDS

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生物活性

Discription

IQ 3 is a selective JNK3 inhibitor (Kd values are 66, 240 and 290 nM for JNK3, JNK1 and JNK2 respectively). Inhibits NF-kB/AP1 transcriptional activity in THP1-Blue cells (IC50 = 1.4 μM). Also inhibits TNF-α and IL-6 production in vitro.

Targets

Target	Value

产品信息

目录号	A16036
分子式	C20H11N3O3
分子量	341.32
CAS号	312538-03-7
SMILES	C1=CC=C2C(=C1)C3=NC4=CC=CC=C4N=C3C2=NOC(=O)C5=CC=CO5
其他名称	IQ3, IQ-3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	9 mg/mL (26.36 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.3 mL	146.49 mL	292.98 mL
0.5 mM	5.86 mL	29.3 mL	58.6 mL
1 mM	2.93 mL	14.65 mL	29.3 mL
5 mM	0.59 mL	2.93 mL	5.86 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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