IQ 3

目录号: A16036

JNK3 inhibitor

IQ 3 Chemical Structure

CAS NO. 312538-03-7

IQ 3 is a selective JNK3 inhibitor (Kd values are 66, 240 and 290 nM for JNK3, JNK1 and JNK2 respectively). Inhibits NF-kB/AP1 transcriptional activity in THP1-Blue cells (IC50 = 1.4 μM). Also inhibits TNF-α and IL-6 production in vitro.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 5,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

IQ 3 is a selective JNK3 inhibitor (Kd values are 66, 240 and 290 nM for JNK3, JNK1 and JNK2 respectively). Inhibits NF-kB/AP1 transcriptional activity in THP1-Blue cells (IC50 = 1.4 μM). Also inhibits TNF-α and IL-6 production in vitro.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.3 mL 146.49 mL 292.98 mL
0.5 mM 5.86 mL 29.3 mL 58.6 mL
1 mM 2.93 mL 14.65 mL 29.3 mL
5 mM 0.59 mL 2.93 mL 5.86 mL

*The above data is based on the productmolecular weight 341.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16036
MECHANISM OF ACTION Inhibitor
M. Wt 341.32
Formula C20H11N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 312538-03-7
Synonyms IQ3, IQ-3
SMILES C1=CC=C2C(=C1)C3=NC4=CC=CC=C4N=C3C2=NOC(=O)C5=CC=CO5

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