IRAK inhibitor 6 (IRAK-IN-6)

Name: IRAK inhibitor 6 (IRAK-IN-6)
SKU: A11460
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A11460

IRAK 抑制剂

IRAK-IN-6，亦称为IRAK抑制剂6，是一种白细胞介素-1受体相关激酶4（IRAK-4）抑制剂。据报道，IRAK-4 对于激活细胞内信号传导级联至关重要，包括 NF-kB 和 MAPK 通路，这些通路对于炎症性细胞因子的产生至关重要。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
5mg	¥805.00	现货
10mg	¥1,225.00	现货
25mg	¥2,135.00	现货
50mg	¥3,150.00	现货
100mg	¥4,270.00	现货
*10mM 1mL in DMSO**	¥910.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription	IRAK-IN-6, also known as IRAK inhibitor 6, is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. IRAK-4 is reported to be essential for the activation of the intracellular signalling cascades including NF-kB and MAPK pathways, which are critical for the production of inflammatory cytokines.

产品信息

目录号	A11460
分子式	C20H20N4O3S
分子量	396.46
CAS号	1042672-97-8
SMILES	O=C(C1=CSC(C2=CC=CN=C2)=N1)NC3=CC=C(N4CCOCC4)C=C3OC
其他名称	IRAK-IN-6, IRAK IN 6, IRAKIN6, IRAK inhibitor 6
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	6 mg/mL (15.13 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.22 mL	126.12 mL	252.23 mL
0.5 mM	5.04 mL	25.22 mL	50.45 mL
1 mM	2.52 mL	12.61 mL	25.22 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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