Irinotecan HCl Trihydrate (Campto)

目录号: A10479

Topoisomerase inhibitor

Irinotecan HCl Trihydrate (Campto) Chemical Structure

CAS NO. 136572-09-3

Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription.

库存: 现货

规格 价格 数量
200 mg
¥ 500.00
10mM * 1mL in DMSO
¥ 610.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription.
Targets
Topo I
In vitro (25°C) DMSO 100 mg/mL (147.67 mM)
Water 1 mg/mL (1.47 mM)
Ethanol 7 mg/mL (10.33 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.77 mL 73.83 mL 147.67 mL
0.5 mM 2.95 mL 14.77 mL 29.53 mL
1 mM 1.48 mL 7.38 mL 14.77 mL
5 mM 0.3 mL 1.48 mL 2.95 mL

*The above data is based on the productmolecular weight 677.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10479
MECHANISM OF ACTION Inhibitor
M. Wt 677.2
Formula C33H38N4O6.HCl.3H2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 136572-09-3
Synonyms CPT 11, Camptosar, Campto, Irinotecan
SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl

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