Irinotecan

目录号: A10478

Topoisomerase I inhibitor

Irinotecan Chemical Structure

CAS NO. 97682-44-5

Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.

库存: 现货

规格 价格 数量
100 mg
¥ 600.00
200 mg
¥ 1,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.
靶点信息
Topo I (LoVo, HT-29 cells)
In vitro (25°C) DMSO 7 mg/mL (11.93 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.04 mL 85.22 mL 170.44 mL
0.5 mM 3.41 mL 17.04 mL 34.09 mL
1 mM 1.7 mL 8.52 mL 17.04 mL
5 mM 0.34 mL 1.7 mL 3.41 mL

*The above data is based on the productmolecular weight 586.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10478
MECHANISM OF ACTION Inhibitor
M. Wt 586.7
Formula C33H38N4O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 97682-44-5
Synonyms Camptosar, CPT-11
SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7

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