Isobavachalcone
目录号: A11453
Akt 抑制剂
Isobavachalcone(Corylifolinin)来源于补骨脂(Psoralea corylifolia Linn.),是一种强效的Akt信号通路抑制剂,能够诱导人类癌细胞的凋亡(抑制OVCAR-8细胞生长,IC50值为7.92微摩尔)。
Discription | Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). | |||||
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Cell Research |
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目录号 | A11453 |
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分子式 | C20H20O4 |
分子量 | 324.37 |
CAS号 | 20784-50-3 |
SMILES | O=C(/C=C/C1=CC=C(C=C1)O)C2=CC=C(C(C/C=C(C)\C)=C2O)O |
其他名称 | Corylifolinin; Isobacachalcone |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 56 mg/mL (172.64 mM) | |
Water | Insoluble | ||
Ethanol | 56 mg/mL (172.64 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 30.83 mL | 154.14 mL | 308.29 mL |
0.5 mM | 6.17 mL | 30.83 mL | 61.66 mL |
1 mM | 3.08 mL | 15.41 mL | 30.83 mL |
5 mM | 0.62 mL | 3.08 mL | 6.17 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2