Ispinesib (SB-715992)
目录号: A10486
KSP 抑制剂
Ispinesib(SB-715992)是一种强效的微管蛋白动力蛋白抑制剂,这种蛋白质对于形成双极性有丝分裂纺锤体和细胞周期通过有丝分裂的进程至关重要。
| Discription | Ispinesib (SB-715992) is a potent inhibitor of kinesin spindle protein, a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis. | |||||
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| 目录号 | A10486 |
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| 分子式 | C30H33ClN4O2 |
| 分子量 | 517.1 |
| CAS号 | 336113-53-2 |
| SMILES | CC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C |
| 其他名称 | Ispinesib mesylate,B-715992,CK 0238273 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 93 mg/mL (179.86 mM) | |
| Water | Insoluble | ||
| Ethanol | 93 mg/mL (179.86 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.34 mL | 96.69 mL | 193.39 mL |
| 0.5 mM | 3.87 mL | 19.34 mL | 38.68 mL |
| 1 mM | 1.93 mL | 9.67 mL | 19.34 mL |
| 5 mM | 0.39 mL | 1.93 mL | 3.87 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2