Ispinesib (SB-715992)

目录号: A10486

KSP Inhibitor

Ispinesib (SB-715992)

Ispinesib (SB-715992) Chemical Structure

CAS NO. 336113-53-2

Ispinesib (SB-715992) is a potent inhibitor of kinesin spindle protein, a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,800.00
100 mg
¥ 8,000.00
10mM * 1mL in DMSO
¥ 2,140.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Ispinesib (SB-715992) is a potent inhibitor of kinesin spindle protein, a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis.
Targets
KSP (HsEg5) (Cell-free assay)
1.7 nM(Ki app)
In vitro DMSO 103 mg/mL (199.2 mM)
Water <1 mg/mL (<1 mM)
Ethanol 103 mg/mL (199.2 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.34 mL 96.69 mL 193.39 mL
0.5 mM 3.87 mL 19.34 mL 38.68 mL
1 mM 1.93 mL 9.67 mL 19.34 mL
5 mM 0.39 mL 1.93 mL 3.87 mL

*The above data is based on the productmolecular weight 517.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10486
MECHANISM OF ACTION Inhibitor
M. Wt 517.1
Formula C30H33ClN4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 336113-53-2
Synonyms Ispinesib mesylate,B-715992,CK 0238273
SMILES CC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C

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