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ISRIB (mix-isomer)

目录号: A13816
PERK 抑制剂
ISRIB(混合异构体)是一种强效且选择性的小分子抑制剂,专门针对 PERK 信号传导(IC50约为5 nM),能够有效地逆转 eIF2α 磷酸化的效果。
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5mg
¥280.00
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10mg
¥490.00
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25mg
¥1,050.00
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50mg
¥1,820.00
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100mg
¥2,660.00
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Discription

ISRIB (mix-isomer) is a potent and selective small molecule inhibitor of PERK signaling (IC50 ~5 nM) that can potently reverse the effects of eIF2α phosphorylation.

产品信息
目录号 A13816
分子式 C22H24Cl2N2O4
分子量 451.34
CAS号 548470-11-7
SMILES Clc1ccc(OCC(=O)NC2CCC(CC2)NC(=O)COc2ccc(Cl)cc2)cc1
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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