ISRIB

目录号: A14302

PERK inhibitor

ISRIB Chemical Structure

CAS NO. 1597403-47-8

ISRIB, the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.

库存: 现货

规格 价格 数量
10 mg
¥ 1,000.00
25 mg
¥ 2,000.00
50 mg
¥ 3,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

ISRIB, the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.
Targets
PERK
5 nM
In vitro DMSO 4 mg/mL (8.86 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.16 mL 110.78 mL 221.56 mL
0.5 mM 4.43 mL 22.16 mL 44.31 mL
1 mM 2.22 mL 11.08 mL 22.16 mL
5 mM 0.44 mL 2.22 mL 4.43 mL

*The above data is based on the productmolecular weight 451.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14302
MECHANISM OF ACTION Inhibitor
M. Wt 451.34
Formula C22H24Cl2N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1597403-47-8
Synonyms N/A
SMILES C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl

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