ISRIB (trans-isomer)

Name: ISRIB (trans-isomer)
SKU: A14302
Price: 175 CNY
Rating: 5 (5 reviews)

目录号: A14302

PERK 抑制剂

5 篇发表文献

ISRIB 是一种效力强大且选择性高的 PERK 抑制剂，其 IC50 为 5 nM。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥665.00	现货
25mg	¥1,330.00	现货
50mg	¥2,345.00	现货
100mg	¥4,270.00	现货
500mg	¥9,275.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用ISRIB (trans-isomer)发表的5篇文献

Le Xu, .et al. , Cell Stem Cell, 2024, Aug 16:S1934-5909(24)00287-X PMID: 39181129

SeungHye Han, .et al. , Nature, 2023, Aug;620(7975):890-897 PMID: 37558881

Zhou W, .et al. , Research Square, 2023, MAY 03

Satoshi Watanabe, .et al. , Proc Natl Acad Sci U S A, 2021, May 18;118(20) PMID: 33972447

Satoshi Watanabe, .et al. , bioRxiv, 2020, February 27

生物活性

Discription

ISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.

Targets

Target	Value

产品信息

目录号	A14302
分子式	C22H24Cl2N2O4
分子量	451.34
CAS号	1597403-47-8
SMILES	C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	4 mg/mL (8.86 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.16 mL	110.78 mL	221.56 mL
0.5 mM	4.43 mL	22.16 mL	44.31 mL
1 mM	2.22 mL	11.08 mL	22.16 mL
5 mM	0.44 mL	2.22 mL	4.43 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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