Istiratumab (M-6495) is a bispecific monoclonal antibody designed to target both the Insulin-like Growth Factor 1 Receptor (IGF-1R) and the ErbB3 receptor. This antibody facilitates the degradation of these receptors via the proteasome pathway, a mechanism that may be critical in modulating cellular growth and survival pathways. Istiratumab is primarily used in cancer research, where it serves as a tool to investigate the role of IGF-1R and ErbB3 in tumor biology and therapeutic response.
Istiratumab (M-6495) is a bispecific monoclonal antibody designed to target both the Insulin-like Growth Factor 1 Receptor (IGF-1R) and the ErbB3 receptor. This antibody facilitates the degradation of these receptors via the proteasome pathway, a mechanism that may be critical in modulating cellular growth and survival pathways. Istiratumab is primarily used in cancer research, where it serves as a tool to investigate the role of IGF-1R and ErbB3 in tumor biology and therapeutic response.
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