Istradefylline (KW-6002)

目录号: A11451

A2A antagonist

Istradefylline (KW-6002) Chemical Structure

CAS NO. 155270-99-8

Istradefylline (KW-6002) is a selective antagonist at the A2A receptor. It has been found to be useful in the treatment of Parkinson's disease.

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 550.00
25 mg
¥ 850.00
50 mg
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Istradefylline (KW-6002) is a selective antagonist at the A2A receptor. It has been found to be useful in the treatment of Parkinson's disease.
Targets
Adenosine A2A receptor
2.2 nM(Ki)
In vitro (25°C) DMSO 6 mg/mL (15.6 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.01 mL 130.07 mL 260.15 mL
0.5 mM 5.2 mL 26.01 mL 52.03 mL
1 mM 2.6 mL 13.01 mL 26.01 mL
5 mM 0.52 mL 2.6 mL 5.2 mL

*The above data is based on the productmolecular weight 384.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11451
MECHANISM OF ACTION Antagonist
M. Wt 384.4
Formula C20H24N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 155270-99-8
Synonyms KW-6002,KW6002
SMILES CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)/C=C/C3=CC(=C(C=C3)OC)OC)C

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