ITF2357 (Givinostat)

目录号: A10488

HDAC 抑制剂

ITF2357 (Givinostat)

ITF2357 (Givinostat) Chemical Structure

CAS NO. 732302-99-7

ITF2357 (Givinostat)是一种HDACS抑制剂,具有潜在的抗炎、抗血管生成和抗肿瘤活性。

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,500.00
100 mg
¥ 7,500.00
10mM * 1mL in DMSO
¥ 1,450.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

ITF2357 (Givinostat)是一种HDACS抑制剂,具有潜在的抗炎、抗血管生成和抗肿瘤活性。
靶点信息
HD1-B (Cell-free assay) HD2 (Cell-free assay) HD1-A (Cell-free assay)
7.5 nM10 nM16 nM
In vitro (25°C) DMSO 95 mg/mL (199.59 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (6.3 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.01 mL 105.04 mL 210.08 mL
0.5 mM 4.2 mL 21.01 mL 42.02 mL
1 mM 2.1 mL 10.5 mL 21.01 mL
5 mM 0.42 mL 2.1 mL 4.2 mL

*The above data is based on the productmolecular weight 476.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10488
作用机制 Inhibitor (抑制剂)
M. Wt 476.0
Formula C24H27N3O4.HCl.H2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 732302-99-7
Synonyms Gavinostat
SMILES CC[NH+](CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO.O.[Cl-]

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