Itraconazole (Sporanox)

Name: Itraconazole (Sporanox)
SKU: A10489
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A10489

1 篇发表文献

伊曲康唑是一种相对强效的CYP3A4抑制剂，其IC50为6.1纳摩尔，用作三唑类抗真菌药物。

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规格	价格	库存
50mg	¥175.00	现货
100mg	¥280.00	现货
250mg	¥560.00	现货
500mg	¥980.00	现货
1g	¥1,820.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Itraconazole (Sporanox)发表的1篇文献

Paul Mark Medina, .et al. , Transl Oncol, 2021, Jan;14(1):100940 PMID: 33221682

生物活性

Discription

Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent.

Targets

Target	Value

产品信息

目录号	A10489
分子式	C35H38Cl2N8O4
分子量	705.65
CAS号	84625-61-6
SMILES	CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@H]5CO[C@](O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl
其他名称	Sporanox
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 7 mg/mL (9.91 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40% PEG 300+10% Tween 80+45% ddH2O	1.66 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.17 mL	70.86 mL	141.71 mL
0.5 mM	2.83 mL	14.17 mL	28.34 mL
1 mM	1.42 mL	7.09 mL	14.17 mL
5 mM	0.28 mL	1.42 mL	2.83 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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