IU1

Name: IU1
SKU: A13209
Price: 175 CNY
Rating: 5 (2 reviews)

目录号: A13209

Usp14 抑制剂

2 篇发表文献

IU1 是一种选择性的 Usp14 抑制剂。它能够抑制体外蛋白酶体相关的 Usp14 的催化活性（IC50 < 4 uM）。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥490.00	现货
25mg	¥665.00	现货
50mg	¥1,225.00	现货
100mg	¥2,065.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用IU1发表的2篇文献

Kevin Bohm, .et al. , Arch Pharm (Weinheim), 2023, Jul;356(7):e2200661 PMID: 37196427

Anurag Rathore, .et al. , Sci Rep, 2020, 10: 5350 PMID: 32210344

生物活性

Discription

IU1 is a selective inhibitor of Usp14. It inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 uM).

Targets

Target	Value

产品信息

目录号	A13209
分子式	C18H21FN2O
分子量	300.37
CAS号	314245-33-5
SMILES	CC1=CC(=C(N1C2=CC=C(C=C2)F)C)C(=O)CN3CCCC3
其他名称	IU-1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	51 mg/mL (169.79 mM)
	Water	Insoluble
	Ethanol	51 mg/mL (169.79 mM)
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.29 mL	166.46 mL	332.92 mL
0.5 mM	6.66 mL	33.29 mL	66.58 mL
1 mM	3.33 mL	16.65 mL	33.29 mL
5 mM	0.67 mL	3.33 mL	6.66 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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