IWP-2

目录号: A12707

Wnt 抑制剂

IWP-2

IWP-2 Chemical Structure

CAS NO. 686770-61-6

IWP-2是Porcn功能的灭活剂和Wnt生成的抑制剂,无细胞试验中IC50为27 nM,并阻止β-catenin的积累。Wnt/b-catenin途径维持使干细胞保持多能性的转录程序。

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 800.00
25 mg
¥ 1,500.00
100 mg
¥ 4,500.00
10mM * 1mL in DMSO
¥ 900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

IWP-2是Porcn功能的灭活剂和Wnt生成的抑制剂,无细胞试验中IC50为27 nM,并阻止β-catenin的积累。Wnt/b-catenin途径维持使干细胞保持多能性的转录程序。
靶点信息
Wnt (Cell-free assay)
27 nM
In vitro DMSO 29 mg/mL (62.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.43 mL 107.16 mL 214.32 mL
0.5 mM 4.29 mL 21.43 mL 42.86 mL
1 mM 2.14 mL 10.72 mL 21.43 mL
5 mM 0.43 mL 2.14 mL 4.29 mL

*The above data is based on the productmolecular weight 466.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12707
作用机制 Inhibitor (抑制剂)
M. Wt 466.6
Formula C22H18N4O2S3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 686770-61-6
Synonyms IWP 2,IWP2
SMILES CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4

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