IWP-2
目录号: A12707
Wnt 抑制剂
IWP-2 是 Porcn 功能的失活剂和 Wnt 产生的抑制剂,能够阻断 beta-catenin 的积累。Wnt/beta-catenin(“典型”)途径维持使干细胞保持多能性的转录程序。
| Discription | IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production, and blocks beta-catenin accumulation. Wnt/b-catenin ('canonical') pathway maintains transcriptional programs that enable stem cells to remain multipotent. | |||||
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| Cell Research |
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| 目录号 | A12707 |
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| 分子式 | C22H18N4O2S3 |
| 分子量 | 466.6 |
| CAS号 | 686770-61-6 |
| SMILES | CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4 |
| 其他名称 | IWP 2,IWP2 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | Insoluble | |
| Water | Insoluble | ||
| Ethanol | DMF: 24mg/mL (51.44 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.43 mL | 107.16 mL | 214.32 mL |
| 0.5 mM | 4.29 mL | 21.43 mL | 42.86 mL |
| 1 mM | 2.14 mL | 10.72 mL | 21.43 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.29 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2