IWR-1-endo

目录号: A12737

Wnt inhibitor

IWR-1-endo Chemical Structure

CAS NO. 1127442-82-3

IWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription.

库存: 现货

规格 价格 数量
10 mg
¥ 700.00
25 mg
¥ 1,500.00
50 mg
¥ 2,500.00
100 mg
¥ 4,500.00
10mM * 1mL in DMSO
¥ 880.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

IWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription.
Targets
Wnt (L-cells expressing Wnt3A)
180 nM
In vitro DMSO 30 mg/mL (73.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.42 mL 122.12 mL 244.24 mL
0.5 mM 4.88 mL 24.42 mL 48.85 mL
1 mM 2.44 mL 12.21 mL 24.42 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12737
MECHANISM OF ACTION Inhibitor
M. Wt 409.44
Formula C25H19N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1127442-82-3
Synonyms N/A
SMILES C1C2C=CC1C3C2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 IWR-1-endo | IWR-1-endo 供应商 | 订购 IWR-1-endo | IWR-1-endo 价格 | IWR-1-endo 生产商 | 订单 IWR-1-endo | IWR-1-endo 代理商 | 购买 1127442-82-3| 1127442-82-3 供应商 | 订购 1127442-82-3 | 1127442-82-3 价格 | 1127442-82-3 生产商 | 订单 1127442-82-3 | 1127442-82-3 代理商|buy IWR-1-endo | IWR-1-endo Supplier | purchase IWR-1-endo | IWR-1-endo cost | IWR-1-endo manufacturer | order IWR-1-endo | IWR-1-endo distributor | buy 1127442-82-3| 1127442-82-3 Supplier | purchase 1127442-82-3 | 1127442-82-3 cost | 1127442-82-3 manufacturer | order 1127442-82-3 | 1127442-82-3 distributor
Rewards