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microtubule 抑制剂

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产品目录号: A11449


产品名 目录号 价格 数量
Ixabepilone 5mg A11449-5
¥ 2,500.00
Ixabepilone 10mg A11449-10
¥ 4,200.00
Ixabepilone 25mg A11449-25
¥ 8,400.00
Ixabepilone 50mg A11449-50
¥ 14,500.00



Ixabepilone is an epothilone B analog





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Ixabepilone 发表的文献 (2)
  • Hoque M, .et al. Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors, Pharmacol Res, 2018, Aug;134:166-178 PMID: 29944980
  • APRIL L. RISINGER, .et al. Breast Cancer Cell Lines Exhibit Differential Sensitivities to Microtubule-targeting Drugs Independent of Doubling Time, Anticancer Res, 2015, Nov; 35(11): 5845每5850. PMID: 26504006

Chemical Information

目录号 A11449
Mechanism of action Inhibitor
分子量 506.7
化学分子式 C27H42N2O5S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 219989-84-1
Synonyms BMS-24755, Azaepothilone , BMS 247550-1
SMILES code C[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C
化学名称 (1R,5S,6S,7R,10S,14S,16S)-6,10-Dihydroxy-1,5,7,9,9-pentamethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14.1.0]heptadecane-8,12-dione


Ixabepilone is an epothilone B analog
microtubule(tubulin stabilising)


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.68 mL 197.36mL
0.5 mM 3.95 mL 19.74 mL 39.47 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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