Izuralimab is a bispecific IgG1 monoclonal antibody designed for simultaneous targeting of the inducible T-cell costimulator (ICOS/CD278) and the programmed death-1 receptor (PD-1). This dual specificity facilitates a coordinated modulation of T-cell responses, enhancing immune activation against tumors while potentially mitigating autoimmune responses. Izuralimab is utilized predominantly in oncological research to investigate therapeutic strategies for enhancing antitumor immunity.
Izuralimab is a bispecific IgG1 monoclonal antibody designed for simultaneous targeting of the inducible T-cell costimulator (ICOS/CD278) and the programmed death-1 receptor (PD-1). This dual specificity facilitates a coordinated modulation of T-cell responses, enhancing immune activation against tumors while potentially mitigating autoimmune responses. Izuralimab is utilized predominantly in oncological research to investigate therapeutic strategies for enhancing antitumor immunity.
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