J-2156
目录号: A19264
SST4 receptor 激动剂
J-2156 是一种高效、选择性的生长抑素受体4型(SST4受体)激动剂,其对人类和大鼠SST4受体的IC50分别为0.05 nM和0.07 nM。J-2156在大鼠中用于缓解同侧后爪的机械性痛觉过敏和机械性痛觉增强的ED50分别为3.7 mg/kg和8.0 mg/kg。
Discription | J-2156 is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC50s of 0.05 nM and 0.07 nM for human and rat SST4 receptors, respectively. The ED50 of J-2156 in rats for the relief of mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws was 3.7 and 8.0 mg/kg, respectively. |
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目录号 | A19264 |
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分子式 | C24H28N4O4S |
分子量 | 468.57 |
CAS号 | 848647-56-3 |
SMILES | O=C(N)[C@@H](NC([C@H](CCN)NS(C1=CC=C(C)C2=CC=CC=C21)(=O)=O)=O)CC3=CC=CC=C3 |
其他名称 | J2156, J 2156 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2