J14
目录号: A22706
sulfiredoxin 抑制剂
J14 是一种可逆的硫氧还蛋白抑制剂,其 IC50 为 8.1 μM。J14 通过抑制硫氧还蛋白,诱导氧化应激(细胞内 ROS 积累),导致细胞毒性和癌细胞死亡。
| Discription | J14 is a reversible sulfiredoxin inhibitor with an IC50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death. |
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| 目录号 | A22706 |
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| 分子式 | C28H25ClN4O2S |
| 分子量 | 517.04 |
| CAS号 | 1043854-13-2 |
| SMILES | O=C(O)C1=CC=C(CSC2=NC(C3=CC=CC=C3)=CC(N4CCN(C5=CC=CC=C5Cl)CC4)=N2)C=C1 |
| 其他名称 | J 14,J-14 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2