JAK3 covalent inhibitor-1

目录号: A18926

JAK3 covalent 抑制剂

JAK3 covalent inhibitor-1

JAK3 covalent inhibitor-1 Chemical Structure

CAS NO. 2300106-50-5

JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.

库存: 现货

规格 价格 数量
1 mg
¥ 3,200.00
5 mg
¥ 9,600.00
10 mg
¥ 16,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.49 mL 222.98 mL
0.5 mM 4.46 mL 22.3 mL 44.6 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18926
作用机制 Inhibitor (抑制剂)
M. Wt 448.47
Formula C22H17FN6O2S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 2300106-50-5
Synonyms 0
SMILES O=S(N[C@H](C[C@@H]1NC#N)C(C1=C2)=CC=C2C3=C4C(NC=C4)=NC=N3)(C5=CC=CC(F)=C5)=O

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