Jervine
目录号: A16221
SMO 抑制剂
Jervine 是一种天然存在的类固醇生物碱，它通过阻断 Sonic Hedgehog (Shh) 信号传导来引起单眼畸形；Jervine 是 Smo 的抑制剂。
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生物活性
| Discription | Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling; Jervine is an inhibitor of Smo. |
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产品信息
| 目录号 | A16221 |
|---|---|
| 分子式 | C27H39NO3 |
| 分子量 | 425.6 |
| CAS号 | 469-59-0 |
| SMILES | CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1 |
| 其他名称 | 11-Ketocyclopamine |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 4 mg/mL (9.39 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.5 mL | 117.48 mL | 234.96 mL |
| 0.5 mM | 4.7 mL | 23.5 mL | 46.99 mL |
| 1 mM | 2.35 mL | 11.75 mL | 23.5 mL |
| 5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 469-59-0 | 469-59-0 供应商 | 469-59-0 花费 | 469-59-0 生产商 | 订购 469-59-0 | 469-59-0 代理商