JG-98

目录号: A18734

Hsp70 inhibitor

JG-98

JG-98 Chemical Structure

CAS NO. 1456551-16-8

JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.

库存: 现货

规格 价格 数量
5 mg
¥ 3,200.00
10 mg
¥ 5,200.00
50 mg
¥ 15,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.
In vitro DMSO 7 mg/mL (13.09 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.71 mL 93.54 mL 187.08 mL
0.5 mM 3.74 mL 18.71 mL 37.42 mL
1 mM 1.87 mL 9.35 mL 18.71 mL
5 mM 0.37 mL 1.87 mL 3.74 mL

*The above data is based on the productmolecular weight 534.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18734
作用机制 Inhibitor (抑制剂)
M. Wt 534.54
Formula C24H21Cl2N3OS3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1456551-16-8
Synonyms JG98, JG 98
SMILES CN1/C(SC2=CC(Cl)=CC=C12)=C3S/C(N(CC)C\3=O)=C\C4=[N+](C=CS4)CC5=CC=CC=C5.[Cl-]

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